Help Extinguish Symptoms

With Gynazole•1®

Gynazole•1® Butoconazole Nitrate Vaginal Cream USP, 2% is a prescription vaginal cream used to treat yeast infections (VVC) in non-pregnant women.

Fast Initial Relief In Just One Dose1 2

  • Rapid initial relief of symptoms (e.g., itching, burning, irritation, discharge, and rash)1,2
    • 75% of women experienced first relief of symptoms within approximately 24 hours1
  • Butoconazole provides antimicrobial activity against Candida pathogens; demonstrated by in vitro data, the 48-hour MIC90 with butoconazole was 0.01 against all species tested including, but not limited to, C albicans, C glabrata, andC tropicalis3
  • Butoconazole has been demonstrated to be clinically effective in infection caused by C albicans
References:
  1. Seidman LS, Skokos CK. An evaluation of butoconazole nitrate 2% Site Release® vaginal cream (Gynazole·1®) compared to fluconazole 150 mg tablets (Diflucan®) in the time to relief of symptoms in patients with vulvovaginal candidiasis. Infect Dis Obstet Gynecol. 2005; 13:197-206.
  2. Brown D, Henzl MR, Kaufman RH; Gynazole 1 Study Group. Butoconazole nitrate 2% for vulvovaginal candidiasis: new, single-dose vaginal cream formulation vs. seven-day treatment with miconazole nitrate. J Reprod Med. 1999;44:933-938.
  3. Lynch ME, Sobel JD. Comparative in vitro activity of antimycotic agents against pathogenic vaginal yeast isolates. J Med Vet Mycol. 1994;32:267-274.
  4. Gynazole·1® Prescribing Information. Perrigo, November 2014.

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